Microsft Research

HLA Completion

This tool takes as input, HLA class I (loci A,B,C) typing data, specified at possibly multiple resolutions (2-digit, 4-digit, or combination of 2-/4-digit alternatives separated by a ‘/’, in either new or old HLA nomenclature) and probabilistically resolves the typing ambiguities (i.e., probabilistically “completes” the data to 4-digit resolution). Details.

Upload HLA data file (file format):
Or paste your input here:

  Ethnicity Prior:      Minimum Probability:       
Phased Results  

Unphased Results  

Errors and Warnings


J. Listgarten, Z. Brumme, C. Kadie, G. Xiaojiang, B. Walker, M. Carrington, P. Goulder, D. Heckerman (2008) Statistical Resolution of Ambiguous HLA Typing Data. PLoS Computational Biology 4(2): e1000016 doi:10.1371/journal.pcbi.1000016

Previous Version: Windows source code and downloadable program